Product Details

Product Information

What you need to know before you use
Efudix Cream
Do not use Efudix Cream:
• if you are allergic to fluorouracil or any
other ingredients in this medicine (listed in
section 6).
• if you are pregnant, think you may be
pregnant, or are breast-feeding.
• if you are using any medicines known
as antiviral nucleosides (e.g. brivudine,
sorivudine). These medicines are usually used
to treat chickenpox or shingles

Warnings and precautions
Talk to your doctor or pharmacist before taking
Efudix Cream:
• if you know that you have reduced or no
activity of the enzyme dihydropyrimidine
dehydrogenase (DPD) (partial or complete
DPD deficiency).
Take special care with Efudix Cream if you:
• are applying this cream around your eyelids,
nose or lips, and avoid contact with the eyes
or mouth (see section 3, “How to use Efudix
Cream”).
• have open cuts. Do not use this cream on open
cuts as this can lead to too much cream being
absorbed into the blood, which very rarely, can
cause side effects.
Do not smoke or go near naked flames – risk of
severe burns. Fabric (clothing, bedding, dressings
etc) that has been in contact with this product
burns more easily and is a serious fire hazard.
Washing clothing and bedding may reduce
product build-up but not totally remove it.
Sunlight may increase the effects of Efudix. This
may result in increased skin reactions. To prevent
this you must try to stay out of direct sunlight as
much as possible while using the cream and must
not use a sunlamp or sun bed.
Exposure to UV-radiation (e.g.) natural sunlight,
tanning salon) should be avoided. Closing
bandages or dressing may increase inflammatory
reactions of the skin.
Children and adolescents
Efudix Cream is not for use in anyone under
18 years of age.
Other medicines and Efudix Cream
Tell your doctor or pharmacist if you are taking,
have recently taken or might take any other
medicines, including medicines obtained without
a prescription. This is very important, as using
more than one medicine at the same time can
strengthen or weaken the effect of the medicines
involved.
In particular, tell your doctor if you are using:
• medicines to treat chickenpox or shingles
(brivudine, sorivudine) or have used them in
the last 4 weeks. These medicines may increase
the possibility of unwanted effects with Efudix cream

Pregnancy, breast-feeding and fertility
Do not use Efudix Cream and tell your doctor if
you are pregnant, think you might be pregnant.
An effective method of contraception must be
used during treatment with Efudix Cream.
If you become pregnant during treatment inform
your doctor immediately and make use of genetic
counselling.
Do not use Efudix Cream and tell your
doctor if you are breast-feeding. If use during
breastfeeding is absolutely necessary, breastfeeding must be discontinued.
The use of Efudix Cream may impair female and
male fertility. Efudix Cream is not recommended
in men attempting to father a child.
Driving and using machines
It is unlikely that the treatment will have any
effect on your ability to drive or use machines

Patient Information leaflet