Differin Cream – Adapalene Cream, 45g

Treatment for acne

Suitable for dry and fair skin

Active ingredient: Adapalene 0.1%

Differin cream is used in the treatment of moderate to severe acne. It contains the active ingredients adapalene.


Differin cream is used in the treatment of moderate to severe acne. It contains the active ingredients adapalene.

Differin Cream – Adapalene Cream, 45g

If you’re struggling with acne, Differin Cream may be just what you need. The active ingredient in Differin, adapalene, has anti-inflammatory effects that can reduce soreness and irritation. Plus, it’s gentle enough for use on dry and fair skin. Whether your acne is on your face, chest, or back, Differin can help clear it up. So why wait? Speak to your doctor about Differin Cream today!

What is Differin Cream

Adapalene cream belongs to a group of medicines called retinoids (which includes tretinoin) and helps to reduce inflammation and black and white head formation on the outer layer of the skin. Adapalene is an advanced third generation retinoid which exhibits many of the same effects as previous generation medicines like tretinoin but is often tolerated better.

Differin Cream Reviews

After using Differin Cream, it’s helpful to let others know about your experience. Reviews of an item help other users know that medicines received have helped the condition it is claimed for, how well the treatment worked or any issues to be aware of. We invite our users to leave a review of both their treatment and of the service provided. Click on the reviews tab to see if there has been feedback on this item.

What is the price of  Differin Cream?

The price of  Differin Cream is £21.50

Where can you buy Differin Cream?

You can buy Differin Cream at Dock Pharmacy Essex UK, UK Online Pharmacy.

Can you buy Differin Cream Over the counter?

Differin Cream is not available to buy over the counter. You need a prescription to buy Differin Cream.






How To Use

Differin Cream should be applied to the acne-affected areas once a day before retiring and after washing. A thin film of cream should be applied, with the fingertips, avoiding the eyes and lips.

Ensure that the affected areas are dry before application

Differin Cream should be applied at night before going to bed.

Delivery Options

Delivery options

All deliveries are subject to the availability of the product and product sale conditions been met.

Order & Collect
Free next-day collection from In-Store

UK Delivery

Standard Delivery within the UK £3.50 Delivery time 3-4 days
First Class Delivery within the UK £5.90 Delivery time 1-2 days
Priority Delivery within the UK £7.10. Next day delivery by 1pm. Order must be placed by 1pm. Priority delivery is only available Monday to Thursday.

Europe Delivery

Standard Delivery within EEC from £12.50 Delivery time up to 5 days depending on the local delivery service within your country.
Expedited Delivery within EEC £39.50 Delivery time 2 days. Delivery by DHL, UPS or TNT.

Rest of the World

Standard Delivery Rest of the World from £16.10 Delivery Time 10 – 15 Days
Expedited Delivery Rest of the World £55.09 Delivery 5 days. Delivery service by DHL, TNT or UPS

For more information see our Shipping Policy or view our Return policy.

Product Details

If a reaction suggesting sensitivity or severe irritation occurs, use of the medication should be discontinued. If the degree of local irritation warrants, patients should be directed to use the medication less frequently, to discontinue use temporarily until symptoms subside or to discontinue use altogether. Differin Cream should not come into contact with the eyes, mouth, angles of the nose or mucous membranes.

If product enters the eye, wash immediately with warm water. The product should not be applied to either broken (cuts and abrasions), sunburnt or eczematous skin, nor should it be used in patients with severe acne, or acne involving large areas of the body.

Exposure to sunlight and artificial UV irradiation, including sunlamps, should be minimised during use of adapalene. Patients who normally experience high levels of sun exposure and those with inherent sensitivity to sun, should be warned to exercise caution. Use of sunscreen products and protective clothing over treated areas is recommended when exposure cannot be avoided.

Methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216) may cause allergic reactions which can possibly be delayed.

Side Effects

Differin may cause the following adverse drug reactions:

Dry skin, skin irritation, skin burning sensation, erythema

Dermatitis contact, skin discomfort, sunburn, pruritus, skin exfoliation, acne

Dermatitis allergic (allergic contact dermatitis), pain of skin, skin swelling, application site burn**, skin hypopigmentation, skin hyperpigmentation

eyelid irritation, eyelid erythema, eyelid pruritus, eyelid swelling

Reporting of suspected adverse reactions:

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme. Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.


Active Ingredient: Adapalene 0.1% w/w.

Patient Information Leaflet

Patient Information Leaflet


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