Description
Collis Brownes Mixture, 45ml
Collis Browne’s Mixture is an oral morphine-and-peppermint-oil medicine used for symptomatic relief of cough and diarrhoea.
Morphine is an opioid with central antitussive activity and gastrointestinal effects that slow intestinal movement. Peppermint oil has gastrointestinal antispasmodic and carminative properties that can help soothe the stomach and reduce flatulence and griping. The 45ml formulation contains 1mg anhydrous morphine equivalent and 1.5 microlitres peppermint oil per 5ml.
Collis Browne’s Mixture 45ml is a traditional oral medicine used for the symptomatic relief of coughs and diarrhoea. Each 5ml contains morphine hydrochloride equivalent to 1mg anhydrous morphine and peppermint oil 1.5 microlitres. Morphine helps reduce cough activity and slows intestinal movement, while peppermint oil helps calm the stomach and relieve flatulence and griping discomfort. Different doses are used depending on whether the medicine is being taken for cough or diarrhoea. The current patient leaflet allows use in adults, elderly people and children over 6 years, with age-specific dosing. Pharmacy medicine – pharmacist review included. Available through Dock Pharmacy, a legitimate, established GPhC-registered UK pharmacy, with professional pharmacist support. Prescription required – pharmacist review included.
Benefits
Helps relieve cough symptoms
Helps relieve symptoms of diarrhoea
Morphine helps reduce the cough reflex
Morphine helps slow intestinal activity during diarrhoea
Peppermint oil helps calm the stomach
Helps relieve flatulence and griping discomfort
Convenient oral liquid formulation
45ml bottle
Separate dosing guidance for cough and diarrhoea
How to Take
For diarrhoea – adults, elderly people and children over 12 years: Take 10–15ml every 4 hours, up to a maximum of three doses.
For diarrhoea – children aged 6–12 years: Give 5ml every 4 hours, up to a maximum of three doses.
For coughs – adults, elderly people and children over 12 years: Take 5–10ml every 4 hours.
For coughs – children aged 6–12 years: Give 5ml every 4 hours.
Do not give to children under 6 years unless specifically instructed by a doctor.
Do not exceed the stated dose.
If symptoms persist, seek medical advice.
Take by mouth only.
Side Effects
Like all medicines, J. Collis Browne’s Mixture can cause side effects, although not everyone experiences them.
Possible side effects include:
Feeling sick
Vomiting
Constipation
Drowsiness
Dry mouth
Difficulty passing urine
Sweating
Headache
Dizziness or vertigo
Changes in heart rate
Palpitations
Low blood pressure
Restlessness or mood changes
Hallucinations
Pinpoint pupils
Allergic reactions such as rash, itching or wheezing
Dependence or addiction with inappropriate or prolonged use
Stop using the medicine and seek advice if significant or unexpected side effects occur.
Cautions
Do not use if you are allergic to any ingredient.
Do not use if you have shallow breathing or significant breathing difficulties.
Do not use during an asthma attack.
Do not use if you have a head injury or persistent headache.
Do not use if you have a blocked intestine or inflammation of the colon or rectum.
Do not use if you have alcohol dependence.
Do not give to children under 6 years unless specifically directed by a doctor.
Avoid alcohol while taking this medicine.
Speak to a doctor or pharmacist before use if you have kidney or liver problems, low blood pressure, prostate problems, hypothyroidism, epilepsy or a history of opioid or painkiller dependence.
Seek advice before combining with sedatives, sleeping tablets, antidepressants, antipsychotics or other medicines that can cause drowsiness.
Ask a doctor or pharmacist before use during pregnancy or breastfeeding.
This product contains alcohol and sugars including sorbitol, sucrose and fructose.
Why Buy from Dock Pharmacy UK?
Legitimate, established GPhC-registered UK pharmacy
GPhC reference number 1091481
Professional pharmacist support
Regulated UK pharmacy supply
Appropriate pharmacist assessment for morphine-containing pharmacy medicines
Access to genuine medicines and healthcare products
Established physical pharmacy premises in Tilbury, Essex
Online pharmacy service
Professional oversight of medicine supply
The General Pharmaceutical Council lists Dock Pharmacy at 128 Dock Road, Tilbury, RM18 7BJ under registration number 1091481. Its published inspection outcome is Standards met.
FAQ
What is Collis Browne’s Mixture used for?
It is used for symptomatic relief of coughs and diarrhoea.
Does Collis Browne’s Mixture contain morphine?
Yes. Each 5ml contains morphine hydrochloride equivalent to 1mg anhydrous morphine.
Does Collis Browne’s Mixture contain peppermint oil?
Yes. Each 5ml contains 1.5 microlitres peppermint oil.
How does Collis Browne’s Mixture help diarrhoea?
Morphine reduces intestinal motility, while peppermint oil helps calm gastrointestinal discomfort and griping.
How does Collis Browne’s Mixture help a cough?
Morphine acts centrally to reduce the cough reflex, helping suppress cough symptoms.
Can Collis Browne’s Mixture help stomach cramps?
The leaflet specifically describes peppermint oil as helping relieve griping and flatulence, and morphine as helping reduce the effects of diarrhoea and griping pains.
Can Collis Browne’s Mixture help with flatulence?
Yes. The patient leaflet states that peppermint oil helps relieve flatulence and griping.
How do you take Collis Browne’s Mixture for diarrhoea?
Adults and children over 12 years take 10–15ml every 4 hours, up to three doses. Children aged 6–12 years take 5ml every 4 hours, up to three doses.
How do you take Collis Browne’s Mixture for a cough?
Adults and children over 12 years take 5–10ml every 4 hours. Children aged 6–12 years take 5ml every 4 hours.
Can children take Collis Browne’s Mixture?
The current leaflet allows use in children aged 6 years and over with age-specific dosing. It should not be given to children under 6 unless a doctor instructs otherwise.
Can Collis Browne’s Mixture cause drowsiness?
Yes. Drowsiness is listed as a possible side effect.
Can I drink alcohol while taking Collis Browne’s Mixture?
No. The leaflet advises avoiding alcohol while taking the medicine.
Does Collis Browne’s Mixture contain alcohol?
Yes. The leaflet states that the medicine contains 2.3% v/v ethanol.
Can Collis Browne’s Mixture cause constipation?
Yes. Constipation is listed as a possible side effect.
Can Collis Browne’s Mixture be addictive?
Morphine is an opioid and the leaflet lists addiction as a possible risk. It should be used only according to the stated dose and for the intended short-term purpose.
Can I take Collis Browne’s Mixture with sleeping tablets?
You should speak to a pharmacist or doctor first. Combining morphine with sedating medicines may increase drowsiness and respiratory-depression risk. The leaflet specifically advises discussing sleeping tablets and tranquillisers with a healthcare professional.
Can I take Collis Browne’s Mixture with antidepressants?
Check with a doctor or pharmacist first. The leaflet lists several antidepressants, including MAOIs and SSRIs, among medicines requiring caution.
Can I take Collis Browne’s Mixture during pregnancy?
Ask a doctor or pharmacist before using the medicine during pregnancy.
Can I take Collis Browne’s Mixture while breastfeeding?
Professional advice is required before use while breastfeeding.
Can people with breathing problems take Collis Browne’s Mixture?
The leaflet states that it should not be used by people with shallow breathing or breathing difficulties, or during an asthma attack.
Does Collis Browne’s Mixture cure diarrhoea?
No. It provides symptomatic relief and does not treat every underlying cause of diarrhoea. Persistent, severe or bloody diarrhoea requires medical assessment.
Does Collis Browne’s Mixture treat a bacterial stomach infection?
No. It is not an antibiotic and should not be presented as treating bacterial gastrointestinal infection.
Does Collis Browne’s Mixture cure a cough?
No. It helps relieve cough symptoms; it does not treat every underlying cause of cough.
What size bottle is J. Collis Browne’s Mixture?
The product is available in 45ml and 100ml bottles. This product page is for the 45ml bottle.
What does J. Collis Browne’s Mixture look like?
The patient leaflet describes it as a dark brown liquid with a peppermint and caramel smell.
Does Collis Browne’s Mixture contain sugar?
Yes. The formulation includes sorbitol solution and treacle containing sucrose and fructose. People with certain sugar intolerances should seek medical advice before use.
Does Collis Browne’s Mixture require a prescription?
It is not routinely a prescription-only medicine, but because it contains morphine it should be supplied through appropriate pharmacy channels with professional oversight.
Where can I buy J. Collis Browne’s Mixture 45ml in the UK?
J. Collis Browne’s Mixture 45ml may be purchased through UK pharmacies subject to stock availability and appropriate pharmacy supply requirements.
Can I buy Collis Browne’s Mixture online in the UK?
Where legally supplied online, it should be obtained from an appropriately registered UK pharmacy and may require pharmacist assessment before supply.
Why buy J. Collis Browne’s Mixture from Dock Pharmacy UK?
Dock Pharmacy is a GPhC-registered UK pharmacy, reference 1091481, providing regulated pharmacy services and professional pharmacy oversight. Its current GPhC inspection page records an overall outcome of Standards met.
Collis Browne’s Mixture is a 45ml oral medicine containing morphine and peppermint oil for relief of coughs and symptoms of diarrhoea. Morphine has antitussive and gastrointestinal-slowing effects, while peppermint oil helps relieve gastrointestinal discomfort, flatulence and griping. The medicine requires different dosing depending on the condition being treated and should not be used in children under 6 years unless specifically directed by a doctor. Available through Dock Pharmacy UK, a GPhC-registered pharmacy.

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