Zonegran 100mg Capsules – Zonisamide, 56 Capsules

The product is only available on prescription of a registered Doctor / Vet and other registered prescribers. You can order this product now, but it will not be shipped until we have received your valid prescription. Once you have ordered we will email you different ways to get your prescription to us.

£85.50

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Zonegran 100mg Capsules – Zonisamide, 56 Capsules

If you’re looking for an antiepileptic medicine that can effectively treat partial seizures, Zonegran is the answer. Zonegran 100mg capsules contain zonisamide, which is a powerful active ingredient that has been proven to be effective in treating partial seizures. In addition, zonisamide is also effective in preventing secondary generalisation, which is when a seizure affects all of the brain. So if you’re looking for a medicine that can effectively treat your partial seizures and prevent them from becoming worse, Zonegran is the perfect choice.

Zonegran 100mg Capsules can also be used to treat cats and dogs.

Zonegran may be used:
• On its own to treat seizures in adults.
• With other antiepileptic medicines to treat seizures in adults, adolescents, and children aged 6 years and above.

Zonegran 100mg Capsules Reviews

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What is the price of  Zonegran 100mg Capsules?

The price of  Zonegran 100mg Capsules is £85.50

Where can you buy Zonegran 100mg Capsules?

You can buy Zonegran 100mg Capsules at Dock Pharmacy Essex UK, UK Online Pharmacy.

Can you buy Zonegran 100mg Capsules Over the counter?

Zonegran 100mg Capsules is not available to buy over the counter. You need a prescription to buy Zonegran 100mg Capsules

Brand

Zonegran

How To Use

How to take Zonegran

Always take this medicine exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.

 

Delivery Options

Delivery options

All deliveries are subject to the availability of the product and product sale conditions been met.

Order & Collect
Free next-day collection from In-Store

UK Delivery

Standard Delivery within the UK £3.50 Delivery time 3-4 days
First Class Delivery within the UK £5.90 Delivery time 1-2 days
Priority Delivery within the UK £7.10. Next day delivery by 1pm. Order must be placed by 1pm. Priority delivery is only available Monday to Thursday.

Europe Delivery

Standard Delivery within EEC from £12.50 Delivery time up to 5 days depending on the local delivery service within your country.
Expedited Delivery within EEC £39.50 Delivery time 2 days. Delivery by DHL, UPS or TNT.

Rest of the World

Standard Delivery Rest of the World from £16.10 Delivery Time 10 – 15 Days
Expedited Delivery Rest of the World £55.09 Delivery 5 days. Delivery service by DHL, TNT or UPS

For more information see our Shipping Policy or view our Return policy.

Product Details

What you need to know before you take Zonegran

Do not take Zonegran: • if you are allergic to zonisamide or any of the other ingredients of this medicine (listed in section 6), • if you are allergic to other sulphonamide medicines. Examples include: sulphonamide antibiotics, thiazide diuretics, and sulfonylurea antidiabetes medicines, • if you are allergic to peanut or soya, do not use this medicinal product. Warnings and precautions Zonegran belongs to a group of medicines (sulphonamides) which can cause severe allergic reactions, severe skin rashes, and blood disorders, which very rarely can be fatal (see section 4. Possible side effects). Serious rashes occur in association with Zonegran therapy, including cases of Stevens-Johnson syndrome. The use of Zonegran may lead to high levels of ammonia in the blood which could lead to a change in brain function, especially if you are also taking other medicines which can increase ammonia levels (for example valproate), have a genetic disorder causing build-up of too much ammonia in the body 2 (urea cycle disorder), or if you have liver problems. Tell your doctor immediately if you become unusually drowsy or confused. Talk to your doctor or pharmacist before taking Zonegran if you: • are younger than 12 years old, as you may be at greater risk of decreased sweating, heat stroke, pneumonia and liver problems. If you are younger than 6 years old, Zonegran is not recommended for you. • are elderly, as your dose of Zonegran may need adjusting, and you may be more likely to develop an allergic reaction, severe skin rash, swelling of the feet and legs, and itchiness when taking Zonegran (see section 4 Possible side effects). • suffer from liver problems, as your dose of Zonegran may need adjusting. • have eye problems such as glaucoma. • suffer from kidney problems as your dose of Zonegran may need adjusting. • have previously suffered from kidney stones, as you may be at increased risk of developing more kidney stones. Reduce the risk of kidney stones by drinking sufficient water. • live in a place or are on holiday in a place where the weather is warm. Zonegran can make you perspire less, which can cause your body temperature to increase. Reduce the risk of overheating by drinking sufficient water and keeping cool. • are underweight, or have lost a lot of weight as Zonegran can cause you to lose more weight. Tell your doctor as this may need to be monitored. • are pregnant or could become pregnant (see section ‘pregnancy, breast-feeding and fertility’ for further information). If any of these applies to you, tell your doctor before you take Zonegran. Children and adolescents Talk to your doctor about the following risks: Preventing overheating and dehydration in children Zonegran can cause your child to sweat less and overheat and if your child is not treated this can lead to brain damage and death. Children are most at risk especially in hot weather. When your child is taking Zonegran: • Keep your child cool especially in hot weather • Your child must avoid heavy exercise especially when the weather is hot • Give your child plenty of cold water to drink • Your child must not take these medicines: carbonic anhydrase inhibitors (like topiramate and acetazolamide), and anticholinergic agents (like clomipramine, hydroxyzine, diphenhydramine, haloperidol, imipramine and oxybutynin). If your child’s skin feels very hot with little or no sweating, becomes confused, has muscle cramps, or your child’s heartbeat or breathing becomes rapid: • Take your child to a cool, shaded place • Sponge your child’s skin with cool (not cold) water • Give your child cold water to drink • Seek urgent medical assistance. • Body weight: You should monitor your child’s weight every month and see your doctor as soon as possible if your child is not gaining enough weight. Zonegran is not recommended for children who are underweight or have a small appetite, and should be used with caution in those below 20 kg. • Increased acid level in the blood and kidney stones: Reduce these risks by ensuring that your child drinks enough water and is not taking any other medicine which could cause kidney stones (see 3 Other medicines). Your doctor will monitor your child’s blood bicarbonate levels and kidneys (see also section 4). Do not give this medicine to children below the age of 6 years because it is not known for this age group whether the potential benefits are greater than the risks. Other medicines and Zonegran Please tell your doctor or pharmacist if you are taking, or have recently taken, any other medicines, including medicines obtained without a prescription. • Zonegran should be used carefully in adults when taken with medicines that can cause kidney stones, like topiramate or acetazolamide. In children, this combination is not recommended • Zonegran could possibly increase your blood levels of medicines like digoxin and quinidine, and so a reduction in their dose may be required. • Other medicines like phenytoin, carbamazepine, phenobarbitone and rifampicin can decrease your blood levels of Zonegran, which may require an adjustment of your dose of Zonegran. Zonegran with food and drink Zonegran can be taken with or without food. Pregnancy, breast-feeding and fertility • If you are pregnant, or think you may be pregnant, you must tell your doctor straight away and discuss possible risks the epilepsy medicine you are taking might pose to your unborn baby. • If you are planning to become pregnant you should discuss your epilepsy treatment with your doctor as early as possible before you become pregnant. • You should not stop your treatment without discussing this with your doctor. Suddenly stopping may lead to breakthrough seizures which may harm you and your unborn baby. It is important that your epilepsy remains well controlled. Pregnancy You must only take zonisamide during your pregnancy if your doctor tells you to. If you are a woman of childbearing age you must use adequate contraception while taking zonisamide and for one month after stopping zonisamide. Studies have shown an increased risk of physical birth abnormalities in children of women taking epilepsy medicines during pregnancy. The risk of physical birth abnormalities may increase when more than one epilepsy medicine is used at the same time. Where possible, your doctor should consider using one epilepsy medicine to control your epilepsy. More research is needed to better understand whether taking zonisamide during pregnancy increases the risk of having a baby born with a physical birth abnormality or a learning or thinking disability. Studies have shown that babies born to mothers using zonisamide during pregnancy were smaller than expected for their age at birth, compared with babies born to mothers treated with lamotrigine monotherapy. Breast-feeding Do not breast-feed whilst taking, or for one month after stopping Zonegran. Fertility There are no clinical data available on the effects of zonisamide on human fertility. Studies in animals have shown changes in fertility parameters. Driving and using machines Zonegran may affect your concentration, ability to react/respond, and may make you feel sleepy, particularly at the beginning of your treatment or after your dose is increased. Be especially careful while driving or operating machinery, if Zonegran affects you in this way. 4 Important information about some of the ingredients of Zonegran Zonegran contains sunset yellow FCF (E110) and allura red AC (E129) Zonegran 100 mg hard capsules contain a yellow colour called sunset yellow FCF (E110) and a red colour called allura red AC (E129), which may cause allergic reactions. Zonegran contains soya oil. If you are allergic to peanut or soya, do not use this medicinal product.

Side Effects

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. Zonegran belongs to a group of medicines (sulphonamides) that can cause severe allergic reactions, severe skin rashes, and blood disorders, which very rarely can be fatal. Contact your doctor immediately if you: • have difficulty breathing, a swollen face, lips or tongue, or a severe skin rash as these symptoms may indicate that you are having a severe allergic reaction. • have signs of overheating – high body temperature but little or no sweating, rapid heartbeat and breathing, muscle cramps, and confusion. • have thoughts of harming or killing yourself. A small number of people being treated with antiepileptics such as Zonegran have had thoughts of harming or killing themselves. • have pain in your muscles or a feeling of weakness, as this may be a sign of abnormal muscle breakdown which can lead to kidney problems. • get a sudden pain in your back or stomach, have pain on urinating (passing water) or notice blood in your urine, as this may be a sign of kidney stones. • develop visual problems such as eye pain or blurred vision while taking Zonegran Contact your doctor as soon as possible if you: • have an unexplained skin rash, as this could develop into a more severe skin rash or skin peeling. • feel unusually tired or feverish, have a sore throat, swollen glands, or find that you bruise more easily, as this may mean you have a blood disorder. • have signs of increased acid level in the blood- headaches, drowsiness, shortness of breath and loss of appetite. Your doctor may need to monitor or treat this. Your doctor may decide that you should stop using Zonegran. The most common side effects of Zonegran are mild. They occur during the first month of treatment and usually decrease with continued treatment. In children ages 6 – 17 years old, side effects were consistent with those described below with the following exceptions: pneumonia, dehydration, sweating decreased (common) and abnormal liver enzymes (uncommon). Very common side effects (may affect more than 1 in 10 people): • agitation, irritability, confusion, depression • poor muscle coordination, dizziness, poor memory, sleepiness, double vision • loss of appetite, decreased blood levels of bicarbonate (a substance that prevents your blood from becoming acidic) Common side effects (may affect up to 1 in 10 people): • difficulty sleeping, strange or unusual thoughts, feeling anxious or emotional. • slowed thoughts, loss of concentration, speech abnormalities, abnormal skin sensation (pins and needles), tremor, involuntary movement of the eyes. • kidney stones. • skin rashes, itching, allergic reactions, fever, tiredness, flu-like symptoms, hair loss. • ecchymosis (a small bruise caused by blood leaking from broken blood vessels in the skin). 6 • loss of weight, nausea, indigestion, stomach pains, diarrhoea (loose stools), constipation. • swelling of the feet and legs. Uncommon side effects (may affect up to 1 in 100 people): • anger, aggression, thoughts of suicide, suicide attempt. • vomiting. • gall bladder inflammation, gallstones. • urinary stones. • lung infection / inflammation, urinary tract infections. • low blood potassium levels, convulsions/seizures. Very rare side effects (may affect up to 1 in 10,000 people): • hallucinations, memory loss, coma, neuroleptic malignant syndrome (inability to move, sweating, fever, incontinence), status epilepticus (prolonged or repeated seizures). • breathing disorders, shortness of breath, inflammation of the lungs. • inflammations of the pancreas (severe pain in the stomach or back) • liver problems, kidney failure, increased blood levels of creatinine (a waste product that your kidneys should normally remove). • severe rashes or skin peeling (at the same time you may feel unwell or develop a fever). • abnormal muscle breakdown (you may feel pain or weakness in your muscles) which can lead to kidney problems. • swollen glands, blood disorders (reduction in the number of blood cells, which can make infection more likely and can make you look pale, feel tired and feverish, and bruise more easily). • decreased sweating, overheating. • glaucoma, which is a blockage of fluid in the eye causing increased pressure in the eye. Eye pain, blurred vision or decreased vision may occur and can be signs of glaucoma. Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly (see details below). By reporting side effects you can help provide more information on the safety of this medicine. United Kingdom Yellow Card Scheme Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App store

Ingredients

The active substance in Zonegran is zonisamide

Zonegran 100 mg hard capsules contain 100 mg zonisamide

The other ingredients that are present in the capsule contents are: microcrystalline cellulose, hydrogenated vegetable oil (from soyabean) and sodium laurilsulfate.

  • The capsule shell contains: gelatin, titanium dioxide (E171), shellac, propylene glycol, potassium hydroxide, black iron oxide (E172). Additionally the 100 mg capsule shell contains sunset yellow FCF (E110) and allura red (E129)

 

How to Store

How to store Zonegran

Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the blister and the carton after EXP. The expiry date refers to the last day of that month. Do not store above 30°C. Do not use this medicine if you notice any damage to the capsules, blister or carton or any visible signs of deterioration in the medicine. Return the pack to your pharmacist. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Patient Information leaflet

Click here for the Patient Information leaflet

Please read before using the product

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