Xarelto 20mg Tablets – Rivaroxaban 20mg Tablets

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XARELTO TAB 20MG

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XARELTO TAB 20MG

Xarelto 20mg Tablets – Rivaroxaban 20mg Tablets

Xarelto 20mg Tablets – Rivaroxaban 20mg Tablets are a prescription medicine used to help prevent blood clots in people who have had a heart attack or stroke, or have certain other heart problems.

Xarelto, its active ingredient Rivaroxaban belongs to a group of medicines called antithrombotic agents. It works by blocking a blood clotting factor (factor Xa) and thus reducing the tendency of the blood to form clots.

Xarelto 20mg Tablets is used in adults to:

  • prevent blood clots in the veins after a hip or knee replacement operation. Your doctor has prescribed this medicine for you because after an operation you are at an increased risk of getting blood clots.
  • treat blood clots in the veins of your legs (deep vein thrombosis) and in the blood vessels of your lungs (pulmonary embolism), and to prevent blood clots from re-occurring in the blood vessels of your legs and/or lungs.

Xarelto is used in children and adolescents below 18 years and with a body weight of 30 kg or more to:

  • treat blood clots and prevent re-occurrence of blood clots in the veins or in the blood vessels of the lungs, following initial treatment of at least 5 days with injectable medicines used to treat blood clots.

Xarelto 20mg Tablets Reviews

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What is the price of  Xarelto 20mg Tablets?

The price of  Xarelto 20mg Tablets starts from £36.54

Where can you buy Xarelto 20mg Tablets?

You can buy Xarelto 20mg Tablets at Dock Pharmacy Essex UK, UK Online Pharmacy.

Can you buy Xarelto 20mg Tablets Over the counter?

Xarelto 20mg Tablets is not available to buy over the counter. You need a prescription to buy Xarelto 20mg Tablets

size

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Brand

Xarelto

How To Use

How to take Xarelto

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

You must take Xarelto together with a meal.

Swallow the tablet(s) preferably with water.

If you have difficulty swallowing the tablet whole, talk to your doctor about other ways to take Xarelto. The tablet may be crushed and mixed with water or apple puree immediately before you take it. This mixture should be immediately followed by food.

If necessary, your doctor may also give you the crushed Xarelto tablet through a stomach tube.

How much to take

  • Adults
    • To prevent blood clots in brain (stroke) and other blood vessels in your body
      The recommended dose is one tablet Xarelto 20 mg once a day.
      If you have kidney problems, the dose may be reduced to one tablet Xarelto 15 mg once a day.
      If you need a procedure to treat blocked blood vessels in your heart (called a percutaneous coronary intervention – PCI with an insertion of a stent), there is limited evidence to reduce the dose to one tablet Xarelto 15 mg once a day (or to one tablet Xarelto 10 mg once a day in case your kidneys are not working properly) in addition to an antiplatelet medicine such as clopidogrel.
    • To treat blood clots in the veins of your legs and blood clots in the blood vessels of your lungs, and for preventing blood clots from re-occurring
      The recommended dose is one tablet Xarelto 15 mg twice a day for the first 3 weeks. For treatment after 3 weeks, the recommended dose is one tablet Xarelto 20 mg once a day.
      After at least 6 months blood clot treatment your doctor may decide to continue treatment with either one 10 mg tablet once a day or one 20 mg tablet once a day.
      If you have kidney problems and take one tablet Xarelto 20 mg once a day, your doctor may decide to reduce the dose for the treatment after 3 weeks to one tablet Xarelto 15 mg once a day if the risk for bleeding is greater than the risk for having another blood clot.
  • Children and adolescents
    The dose of Xarelto depends on the body weight, and will be calculated by the doctor.

    • The recommended dose for children and adolescents with a body weight between 30 kg and less than 50 kg is one Xarelto 15 mg tablet once a day.
    • The recommended dose for children and adolescents with a body weight of 50 kg or more is one Xarelto 20 mg tablet once a day.

    Take each Xarelto dose with a drink (e.g. water or juice) during a meal. Take the tablets every day at approximately the same time. Consider setting an alarm to remind you.
    For parents or caregivers: please observe the child to ensure the full dose is taken.
    As the Xarelto dose is based on body weight it is important to keep scheduled doctor’s visits because the dose may need to be adjusted as the weight changes.
    Never adjust the dose of Xarelto by yourself. The doctor will adjust the dose if necessary.
    Do not split the tablet in an attempt to provide a fraction of a tablet dose. If a lower dose is required please use the alternative presentation of Xarelto granules for oral suspension.
    For children and adolescents who are unable to swallow tablets whole, please use Xarelto granules for oral suspension.
    If the oral suspension is not available, you may crush the Xarelto tablet and mix with water or apple puree immediately before taking. Take some food after taking this mixture. If necessary, your doctor may also give the crushed Xarelto tablet through a stomach tube.
    If you spit up the dose or vomit

    • less than 30 minutes after you have taken Xarelto, take a new dose.
    • more than 30 minutes after you have taken Xarelto, do not take a new dose. In this case, take the next Xarelto dose at the usual time.

    Contact the doctor if you repeatedly spit up the dose or vomit after taking Xarelto.

 

When to take Xarelto

Take the tablet(s) every day until your doctor tells you to stop.

Try to take the tablet(s) at the same time every day to help you to remember it.

Your doctor will decide how long you must continue treatment.

To prevent blood clots in the brain (stroke) and other blood vessels in your body:

If your heart beat needs to be restored to normal by a procedure called cardioversion, take Xarelto at the times your doctor tells you.

If you forget to take Xarelto

  • Adults, children and adolescents:
    If you are taking one 20 mg tablet or one 15 mg tablet once a day and have missed a dose, take it as soon as you remember. Do not take more than one tablet in a single day to make up for a forgotten dose. Take the next tablet on the following day and then carry on taking one tablet once a day.
  • Adults:
    If you are taking one 15 mg tablet twice a day and have missed a dose, take it as soon as you remember. Do not take more than two 15 mg tablets in a single day. If you forget to take a dose you can take two 15 mg tablets at the same time to get a total of two tablets (30 mg) on one day. On the following day you should carry on taking one 15 mg tablet twice a day.

 

If you take more Xarelto than you should

Contact your doctor immediately if you have taken too many Xarelto tablets. Taking too much Xarelto increases the risk of bleeding.

If you stop taking Xarelto

Do not stop taking Xarelto without talking to your doctor first, because Xarelto treats and prevents serious conditions.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Delivery Options

Delivery options

All deliveries are subject to the availability of the product and product sale conditions been met.

Order & Collect
Free next-day collection from In-Store

UK Delivery

Standard Delivery within the UK £3.50 Delivery time 3-4 days
First Class Delivery within the UK £5.90 Delivery time 1-2 days
Priority Delivery within the UK £7.10. Next day delivery by 1pm. Order must be placed by 1pm. Priority delivery is only available Monday to Thursday.

Europe Delivery

Standard Delivery within EEC from £12.50 Delivery time up to 5 days depending on the local delivery service within your country.
Expedited Delivery within EEC £39.50 Delivery time 2 days. Delivery by DHL, UPS or TNT.

Rest of the World

Standard Delivery Rest of the World from £16.10 Delivery Time 10 – 15 Days
Expedited Delivery Rest of the World £55.09 Delivery 5 days. Delivery service by DHL, TNT or UPS

For more information see our Shipping Policy or view our Return policy.

Product Details

What you need to know before you take Xarelto

Do not take Xarelto

  • if you are allergic to rivaroxaban or any of the other ingredients of this medicine (listed in section 6)
  • if you are bleeding excessively
  • if you have a disease or condition in an organ of the body that increases the risk of serious bleeding (e.g. stomach ulcer, injury or bleeding in the brain, recent surgery of the brain or eyes)
  • if you are taking medicines to prevent blood clotting (e.g. warfarin, dabigatran, apixaban or heparin), except when changing anticoagulant treatment or while getting heparin through a venous or arterial line to keep it open.
  • if you have a liver disease which leads to an increased risk of bleeding
  • if you are pregnant or are breast-feeding

 

Do not take Xarelto and tell your doctor if any of these apply to you.

Warnings and precautions

Talk to your doctor or pharmacist before taking Xarelto.

Take special care with Xarelto

  • if you have an increased risk of bleeding, as could be the case in situations such as:
    • severe kidney disease for adults, and moderate or severe kidney disease for children and adolescents, since your kidney function may affect the amount of medicine that works in your body
    • if you are taking other medicines to prevent blood clotting (e.g. warfarin, dabigatran, apixaban or heparin), when changing anticoagulant treatment or while getting heparin through a venous or arterial line to keep it open (see section “Other medicines and Xarelto”)
    • bleeding disorders
    • very high blood pressure, not controlled by medical treatment
    • diseases of your stomach or bowel that might result in bleeding, e.g. inflammation of the bowels or stomach, or inflammation of the oesophagus (gullet), e.g. due to gastroesophageal reflux disease (disease where stomach acid goes upwards into the oesophagus) or tumours located in the stomach or bowels or genital tract or urinary tract
    • a problem with the blood vessels in the back of your eyes (retinopathy)
    • a lung disease where your bronchi are widened and filled with pus (bronchiectasis), or previous bleeding from your lung
  • if you have a prosthetic heart valve
  • if you know that you have a disease called antiphospholipid syndrome (a disorder of the immune system that causes an increased risk of blood clots), tell your doctor who will decide if the treatment may need to be changed.
  • if your doctor determines that your blood pressure is unstable or another treatment or surgical procedure to remove the blood clot from your lungs is planned

 

If any of the above apply to you, tell your doctor before you take Xarelto. Your doctor will decide, if you should be treated with this medicine and if you should be kept under closer observation.

If you need to have an operation

  • it is very important to take Xarelto before and after the operation exactly at the times you have been told by your doctor.
  • If your operation involves a catheter or injection into your spinal column (e.g. for epidural or spinal anaesthesia or pain reduction):
    • it is very important to take Xarelto before and after the injection or removal of the catheter exactly at the times you have been told by your doctor
    • tell your doctor immediately if you get numbness or weakness of your legs or problems with your bowel or bladder after the end of anaesthesia, because urgent care is necessary.

 

Children and adolescents

Xarelto tablets are not recommended for children with a body weight below 30 kg.

There is not enough information on the use of Xarelto in children and adolescents in the adult indications.

Other medicines and Xarelto

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription.

  • If you are taking
    • some medicines for fungal infections (e.g. fluconazole, itraconazole, voriconazole, posaconazole), unless they are only applied to the skin
    • ketoconazole tablets (used to treat Cushing’s syndrome – when the body produces an excess of cortisol)
    • some medicines for bacterial infections (e.g. clarithromycin, erythromycin)
    • some anti-viral medicines for HIV / AIDS (e.g. ritonavir)
    • other medicines to reduce blood clotting (e.g. enoxaparin, clopidogrel or vitamin K antagonists such as warfarin and acenocoumarol)
    • anti-inflammatory and pain relieving medicines (e.g. naproxen or acetylsalicylic acid)
    • dronedarone, a medicine to treat abnormal heart beat
    • some medicines to treat depression (selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs))

    If any of the above apply to you, tell your doctor before taking Xarelto, because the effect of Xarelto may be increased. Your doctor will decide, if you should be treated with this medicine and if you should be kept under closer observation.
    If your doctor thinks that you are at increased risk of developing stomach or bowel ulcers, he may also use a preventative ulcer treatment.

  • If you are taking
    • some medicines for treatment of epilepsy (phenytoin, carbamazepine, phenobarbital)
    • St John’s Wort (Hypericum perforatum), a herbal product used for depression
    • rifampicin, an antibiotic

    If any of the above apply to you, tell your doctor before taking Xarelto, because the effect of Xarelto may be reduced. Your doctor will decide, if you should be treated with Xarelto and if you should be kept under closer observation.

 

Pregnancy and breast-feeding

Do not take Xarelto if you are pregnant or breast-feeding. If there is a chance that you could become pregnant, use a reliable contraceptive while you are taking Xarelto. If you become pregnant while you are taking this medicine, tell your doctor immediately, who will decide how you should be treated.

Driving and using machines

Xarelto may cause dizziness (common side effect) or fainting (uncommon side effect) (see section 4, “Possible side effects”). You should not drive, ride a bicycle or use any tools or machines if you are affected by these symptoms.

Xarelto contains lactose and sodium

If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially “sodium-free”.

Side Effects

Possible side effects

Like all medicines, Xarelto can cause side effects, although not everybody gets them.

Like other similar medicines to reduce the formation of blood clots, Xarelto may cause bleeding which may potentially be life threatening. Excessive bleeding may lead to a sudden drop in blood pressure (shock). In some cases the bleeding may not be obvious.

Tell your doctor immediately if you or the child experience any of the following side effects:

  • Signs of bleeding
    • bleeding into the brain or inside the skull (symptoms can include headache, one-sided weakness, vomiting, seizures, decreased level of consciousness, and neck stiffness. A serious medical emergency. Seek medical attention immediately!)
    • long or excessive bleeding
    • exceptional weakness, tiredness, paleness, dizziness, headache, unexplained swelling, breathlessness, chest pain or angina pectoris

    Your doctor may decide to keep you under closer observation or change the treatment.

  • Signs of severe skin reactions
    • spreading intense skin rash, blisters or mucosal lesions, e.g. in the mouth or eyes (Stevens-Johnson syndrome/toxic epidermal necrolysis).
    • a drug reaction that causes rash, fever, inflammation of internal organs, blood abnormalities and systemic illness (DRESS syndrome).

    The frequency of these side effects is very rare (up to 1 in 10,000 people).

  • Signs of severe allergic reactions
    • swelling of the face, lips, mouth, tongue or throat; difficulty swallowing; hives and breathing difficulties; sudden drop in blood pressure.

    The frequencies of severe allergic reactions are very rare (anaphylactic reactions, including anaphylactic shock; may affect up to 1 in 10,000 people) and uncommon (angioedema and allergic oedema; may affect up to 1 in 100 people).

 

Overall list of possible side effects found in adults, children and adolescents

Common (may affect up to 1 in 10 people)

  • reduction in red blood cells which can make the skin pale and cause weakness or breathlessness
  • bleeding in the stomach or bowel, urogenital bleeding (including blood in the urine and heavy menstrual bleeding), nose bleed, bleeding in the gum
  • bleeding into the eye (including bleeding from the whites of the eyes)
  • bleeding into tissue or a cavity of the body (haematoma, bruising)
  • coughing up blood
  • bleeding from the skin or under the skin
  • bleeding following an operation
  • oozing of blood or fluid from surgical wound
  • swelling in the limbs
  • pain in the limbs
  • impaired function of the kidneys (may be seen in tests performed by your doctor)
  • fever
  • stomach ache, indigestion, feeling or being sick, constipation, diarrhoea
  • low blood pressure (symptoms may be feeling dizzy or fainting when standing up)
  • decreased general strength and energy (weakness, tiredness), headache, dizziness
  • rash, itchy skin
  • blood tests may show an increase in some liver enzymes

 

Uncommon (may affect up to 1 in 100 people)

  • bleeding into the brain or inside the skull (see above, signs of bleeding)
  • bleeding into a joint causing pain and swelling
  • thrombocytopenia (low number of platelets, which are cells that help blood to clot)
  • allergic reactions, including allergic skin reactions
  • impaired function of the liver (may be seen in tests performed by your doctor)
  • blood tests may show an increase in bilirubin, some pancreatic or liver enzymes or in the number of platelets
  • fainting
  • feeling unwell
  • faster heartbeat
  • dry mouth
  • hives

 

Rare (may affect up to 1 in 1,000 people)

  • bleeding into a muscle
  • cholestasis (decreased bile flow), hepatitis incl. hepatocellular injury (inflamed liver incl. liver injury)
  • yellowing of the skin and eye (jaundice)
  • localised swelling
  • collection of blood (haematoma) in the groin as a complication of the cardiac procedure where a catheter is inserted in your leg artery (pseudoaneurysm)

 

Not known (frequency cannot be estimated from the available data)

  • kidney failure after a severe bleeding
  • increased pressure within muscles of the legs or arms after a bleeding, which leads to pain, swelling, altered sensation, numbness or paralysis (compartment syndrome after a bleeding)

 

Side effects in children and adolescents

In general, the side effects observed in children and adolescents treated with Xarelto were similar in type to those observed in adults and were primarily mild to moderate in severity.

Side effects that were observed more often in children and adolescents:

Very common (may affect more than 1 in 10 people)

  • headache
  • fever
  • nose bleeding
  • vomiting

 

Common (may affect up to 1 in 10 people)

  • raised heartbeat
  • blood tests may show an increase in bilirubin (bile pigment)
  • thrombocytopenia (low number of platelets which are cells that help blood to clot)
  • heavy menstrual bleeding

 

Uncommon (may affect up to 1 in 100 people)

  • blood tests may show an increase in a subcategory of bilirubin (direct bilirubin, bile pigment)

 

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme, Website: https://yellowcard.mhra.gov.uk or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects, you can help provide more information on the safety of this medicine.

Ingredients

What Xarelto contains

  • The active substance is rivaroxaban. Each tablet contains 20mg of rivaroxaban.
  • The other ingredients are:
    Tablet core: microcrystalline cellulose, croscarmellose sodium, lactose monohydrate, hypromellose (2910), sodium laurilsulfate, magnesium stearate. See section 2 “Xarelto contains lactose and sodium”
    Tablet film coat: macrogol (3350), hypromellose (2910), titanium dioxide (E 171), iron oxide red (E 172).

How to Store

How to store Xarelto

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton and on each blister or bottle after EXP.

The expiry date refers to the last day of that month.

This medicine does not require any special storage conditions.

Crushed tablets

Crushed tablets are stable in water or apple puree for up to 4 hours.

Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Patient Information leaflet

Click here for the Patient Information leaflet

Please read before using the product

1 review for Xarelto 20mg Tablets – Rivaroxaban 20mg Tablets

    • 5 out of 5
    Xarelto 20mg Tablets – Rivaroxaban 20mg Tablets

    Nicola R. (verified owner)

    Alongside other tablets have worked wonders in my dog via vet prescription

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