Syndol Tablet, 30 Tablets


Syndol Original Tablet, 30 Tablets

Syndol Tablets contains four different medicines called caffeine, codeine phosphate, doxylamine succinate and paracetamol. Paracetamol acts as an analgesic (painkiller) and an antipyretic (lowers body temperature), codeine phosphate is an analgesic, doxylamine succinate is an antihistamine and caffeine is a mild stimulant.

Syndol Tablets is used for the short term treatment of acute moderate pain which is not relieved by paracetamol, ibuprofen and aspirin alone such as headache, including muscle contraction or tension headache, migraine, neuralgia, period pain, toothache and other dental pain, muscular and rheumatic aches and pains and for pain relief following surgery or dental procedures.


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Syndol Tablet, 30 Tablets

Syndol tablet can only be used for the short term treatment of acute moderate pain when other painkillers have not worked.

  • You should only take Syndol original for a maximum of 3 days at a time. If you need to take it for longer than three days you should see your doctor or pharmacist for advice
  • Syndol original contains codeine which can cause addiction if you take it continuously for more than 3 days. This can give you withdrawal symptoms from the medicine when you stop taking it
  • If you take Syndol Original for headaches for more than 3 days it can make them worse
  • Syndol should not be taken by children below the age of 12, due to the risk of severe breathing problems.

Syndol Original Tablet, 30 Tablets

Syndol Tablets contains four different medicines called caffeine, codeine phosphate, doxylamine succinate and paracetamol. Paracetamol acts as an analgesic (painkiller) and an antipyretic (lowers body temperature), codeine phosphate is an analgesic, doxylamine succinate is an antihistamine and caffeine is a mild stimulant.

Syndol Tablets is used for the short term treatment of acute moderate pain which is not relieved by paracetamol, ibuprofen and aspirin alone such as headache, including muscle contraction or tension headache, migraine, neuralgia, period pain, toothache and other dental pain, muscular and rheumatic aches and pains and for pain relief following surgery or dental procedures.

How To Use

How To Use Syndol Tablet

Adults, including the elderly

  • Take one or two tablets every four to six hours as needed for relief
  • Adults should wait at least 4 hours before taking another dose
  • Do not take more than eight tablets in a 24 hour period
  • Do not exceed the stated dose

If you are elderly or of a weakened state you should seek advice from your doctor before taking Syndol as dosage adjustment may be required.

Children aged 16 to 18 years

1 to 2 tablets every 6 hours when necessary up to a maximum of 8 tablets in 24 hours

Children aged 12 to 15 years

1 tablet every 6 hours when necessary up to a maximum of 4 tablets in 24 hours

 

Warning

WHAT YOU NEED TO KNOW BEFORE YOU TAKE SYNDOL TABLET

  • This medicine contains codeine which can cause addiction if you take it continuously for more than 3 days. This can give you withdrawal symptoms from the medicine when you stop taking it
  • If you take this medicine for headaches for more than 3 days it can make them worse

Do not take Syndol if

  • you are allergic to codeine, paracetamol, doxylamine succinate, caffeine or any of the ingredients of this medicine (listed in section 6). Signs of an allergic reaction include a rash and breathing problems. There can also be swelling of the legs, arms, face, throat or tongue
  • you are having an asthma attack or have severe breathing problems
  • you have recently had a head injury
  • you have been told by your doctor that you have increased pressure in your head. Signs of this include headaches, being sick (vomiting) and blurred eyesight
  • you have recently had an operation on your liver, gall bladder or bile duct (biliary tract)
  • you are at risk of blocked intestine (paralytic ileus)
  • you are taking other medicines containing codeine or any other paracetamol-containing products
  • you are taking a medicine of the class known as Monoamine Oxidase Inhibitors (MAOIs, e.g. selegiline, moclobemide), which are used as antidepressants, or if you had taken any medicine of this group in the past 14 days.
  • you are an alcoholic
  • the person going to take the tablets is under 12 years of age
  • you are under 18 years of age and have had your tonsils or adenoids removed due to Obstructive Sleep Apnoea Syndrome
  • you know that you metabolise very rapidly codeine into morphine
  • you are breast-feeding or planning to breastfeed

Do not take Syndol if any of the above apply to you.

Warnings and precautions

Talk to your doctor or pharmacist before taking Syndol if:

  • You have liver, kidney, thyroid or heart problems and/or are elderly or of a weakened state;
  • You have high blood pressure, problems with the prostate gland, obstructive bowel problems, acute abdominal conditions (e.g. peptic ulcer), hormonal problems, problems passing urine or have had recent gastrointestinal surgery;
  • You are in shock, have gallstones, glaucoma, or a disease called myasthenia gravis (a condition which weakens muscles) or a history of fits;
  • You have a history of mood swings, alcohol or drug abuse or are under psychiatric treatment;
  • You are taking a benzodiazepine (used for treatment of anxiety or sleep disorders ), e.g. diazepam, clobazam, lorazepam, chlordiazepoxide, oxazepam, temazepam, nitrazepam, loprazolam, lormetazepam or clonazepam

Codeine is transformed to morphine in the liver by an enzyme. Morphine is the substance that produces pain relief. Some people have a variation of this enzyme and this can affect people in different ways. In some people, morphine is not produced or produced in very small quantities, and it will not provide enough pain relief. Other people are more likely to get serious side effects because a very high amount of morphine is produced. If you notice any of the following side effects, you must stop taking this medicine and seek immediate medical advice: slow or shallow breathing, confusion, sleepiness, small pupils, feeling or being sick, constipation, lack of appetite.

If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking this medicine.

Other medicines and Syndol

Tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines obtained without a prescription, including herbal medicines. This is because Syndol can affect the way some other medicines work. Also, some other medicines can affect the way Syndol works.

While taking Syndol you should not take any other medicines which contain paracetamol.

This includes some painkillers, cough and cold remedies. It also includes a wide range of medicines available from your doctor and more widely in shops.

Do not take this medicine and tell your doctor or pharmacist if you are taking

  • Medicines to treat depression called MAOIs (monoamine oxidase inhibitors) or have recently taken them in the last two weeks. MAOIs are medicines such as moclobemide, phenelzine, tranylcypromine.

Tell your doctor or pharmacist if you are taking or have recently taken any of the following medicines:

  • Medicines which make you drowsy or sleepy (CNS depressants) (e.g. barbiturates, anaesthetics, hypnotics, other opioid analgesics, anxiolytic sedatives, antipsychotics, tricyclic antidepressants and phenothiazines) or a benzodiazepine used to treat anxiety or sleep disorders
  • Medicines for the treatment of high blood pressure (diuretics and antihypertensives)
  • Medicines to treat or prevent clinical depression (antidepressants)
  • Medicines used to treat mental distress or disorder (antipsychotics)
  • Any of the group called antimuscarinics (e.g. atropine, hyoscine)
  • Any of the group called neuromuscular blockers (e.g. tubocurarine)
  • Medicines used to thin the blood such as warfarin (or other coumarins)
  • Metoclopramide or domperidone – used to stop you feeling sick (nausea) or being sick (vomiting)
  • Colestyramine – for lowering blood cholesterol levels
  • Hydroxyzine – to treat anxiety and tension
  • Mexiletine – to treat irregular heartbeat
  • Kaolin or loperamide – for the treatment of diarrhoea
  • Naloxone – to treat a narcotic overdose
  • Naltrexone – used as part of a treatment program for drug or alcohol dependence
  • Cimetidine – to treat stomach ulcers
  • Cisapride – to treat gastro-oesophageal reflux disease
  • Quinidine – to treat irregular heart rate
  • The oral contraceptive pill

If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Syndol.

Concomitant use of opioids and benzodiazepines increases the risk of drowsiness, difficulties in breathing (respiratory depression), coma and may be life-threatening. Because of this, you should only take these together if prescribed by a doctor. Please follow your doctor’s dosage recommendation closely. It could be helpful to inform friends or relatives to be aware of signs and symptoms stated above. Contact your doctor when experiencing such symptoms.

Taking Syndol with food and drink

Avoid alcohol whilst taking Syndol.

Side Effects

POSSIBLE SIDE EFFECTS OF SYNDOL TABLETS

Like all medicines, this medicine can cause side effects, although not everybody gets them. The following side effects may happen with this medicine:

Stop taking Syndol TABLETS and see a doctor or go to a hospital straight away if:

  • You have a rash, fever, swelling, bruising or tiredness
  • You have difficulty in breathing or you feel dizzy
  • You get swelling of the hands, feet, ankles, face, lips or throat which may cause difficulty in swallowing or breathing
    You could also notice an itchy, lumpy rash (hives) or nettle rash (urticaria). This may mean you are having an allergic reaction
  • You get serious skin reactions. Very rare cases have been reported.

Talk to your doctor straight away if you notice the following serious side effects:

  • Severe stomach pain, which may reach to your back. This could be a sign of inflammation of the pancreas (pancreatitis). This is a very rare side effect.
  • You get infections or bruise more easily than usual. This could be because of a blood problem (such as agranulocytosis or thrombocytopenia)
  • Yellowing of the skin or the whites of the eyes

Tell your doctor or pharmacist if any of the following side effects gets serious or lasts longer than a few days:

  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Low blood pressure (causing light-headedness or fainting when standing up)
  • Confusion
  • Depression
  • Difficulties sleeping
  • Shaking, fits
  • Irregular heart beat
  • Stomach pain
  • Sweating
  • Facial flushing
  • General discomfort
  • Loss of appetite
  • Very slow or shallow breathing
  • Shortness of breath
  • Hallucinations, nightmares
  • Cramps or stiffness
  • Becoming dependent on codeine

Other effects that may occur are; constipation, headache, drowsiness, dizziness, restlessness, difficulties passing urine, dry mouth, blurred vision, diarrhoea, thick phlegm.

How do I know if I’m addicted?

If you take the medicine according to the instructions on the pack it is unlikely that you will become addicted to the medicine. However if the following apply to you it is important that you talk to your doctor:

  • You need to take the medicine for longer periods of time
  • You need to take more than the recommended dose
  • When you stop taking the medicine you feel very unwell but you feel better if you start taking the medicine again.

Ingredient

Ingredients

Syndol Tablets

Paracetamol, Codeine Phosphate, Doxylamine Succinate and Caffeine

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