Nardil contains the active ingredient phenelzine, which belongs to a group of medicines called monoamine oxidase inhibitors, or MAOIs.
Nardil is used to treat certain types of depression. It works by changing the way messages are sent from one nerve to another in the brain. Nardil is especially helpful when:
Nardil patient information leaflet
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Nardil Tablets is used to treat certain types of depression:
The usual starting dose is one tablet three times a day. Your doctor will decide what dose is best for you. Follow the instructions on the label and do not change the dose unless your doctor tells you to.
Swallow the tablets with some water. You can take them with or without food.
Your blood pressure should be checked frequently by your doctor and Nardil should be stopped if palpitations or frequent headaches occur.
Nardil tablets contains the active ingredient phenelzine, which belongs to a group of medicines called monoamine oxidase inhibitors, or MAOIs.
Do not take Nardil 15mg Tablets and tell your doctor or pharmacist if any of the following applies to you:
If any of these apply to you, tell your doctor or pharmacist before taking Nardil tablets.
Take special care with Nardil tablets
You should consult your doctor or pharmacist before taking Nardil if you have any of the following conditions:
Your blood pressure should be monitored frequently by your doctor and Nardil should be stopped if palpitations or frequent headaches occur.
Taking other medicines
Please tell your doctor, dentist or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
In particular, tell your doctor if you are taking any of the following medicines, because Nardil may interact with them:
If you are not sure which medicines you are already taking, please ask your doctor or pharmacist.
Taking Nardil Tablets with food and drink
Nardil tablets react with a substance called tyramine which is found in some foods and drinks (see lists below).
If you eat or drink anything containing tyramine while you are taking Nardil, or within 14 days of taking Nardil, you may have a very severe rise in blood pressure.
This will happen soon after eating the food and you may get a violent headache, pounding heart, stiff neck, flushing, sweating or you may be sick. The severity of the reaction depends on the amount of tyramine you eat and may be mild or could be dangerous, even fatal.
If you feel such a reaction happening, tell your doctor or go to your nearest hospital accident and emergency department immediately.
Do not eat:
Cheese (cooked or plain), liver, yoghurt, yeast/meat extracts (e.g. Marmite, Oxo, Bovril or Brewer’s yeast), flavoured textured vegetable protein, broad bean pods, protein which has been allowed to age, degrade or ferment (e.g. hung game, pickled herrings or dry sausage such as salami or pepperoni), fermented soya bean extract, excessive amounts of chocolate.
Do not drink:
Alcohol, non-alcoholic beer, lager or wine. You may drink a reasonable amount of tea or coffee but not to excess.
Pregnancy and breast-feeding
Nardil is not recommended for use during pregnancy, especially during the first and last trimesters. If you are pregnant, think you might be pregnant or are planning to become pregnant, you should talk to your doctor.
Do not breast-feed if you are taking Nardil.
As with any medicine, ask your doctor or pharmacist for advice.
Driving and using machines
Nardil might cause drowsiness or blurred vision. Do not drive or operate machinery until you know if the tablets affect you in this way.
Important information about some of the ingredients of Nardil Tablets
Sunset yellow (E110), a colouring agent in the film coating of Nardil, may cause an allergic reaction.
Side effects are usually mild or moderate in severity and tend to disappear as treatment continues.
The most serious side effects are high blood pressure, which usually happens when the wrong food is eaten (see Section 2 “Taking Nardil Tablets with food and drink”), and neuroleptic malignant syndrome (a serious, sometime life-threatening, condition which results in fever, faster breathing and pulse rate, sweating, muscle stiffness, changes in blood pressure and reduced consciousness). If you feel this is happening to you, STOP TAKING the tablets and tell your doctor or go to your nearest hospital accident and emergency department immediately.
Common side effects are:
Uncommon side effects are:
Very rarely, other serious effects have been seen, these are:
Too little sodium (salt) in the blood has been seen with all types of antidepressants. This may cause drowsiness, confusion or fits. It is more usually seen in the elderly.
If any of these side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor.
Thoughts of suicide and worsening of your depression or anxiety disorder
If you are depressed and/or have anxiety disorders you can sometimes have thoughts of harming or killing yourself. These may be increased when first starting antidepressants, since these medicines all take time to work, usually about two weeks but sometimes longer.
You may be more likely to think like this:
If you have thoughts of harming or killing yourself at any time, contact your doctor or go to a hospital straight away.
You may find it helpful to tell a relative or close friend that you are depressed or have an anxiety disorder, and ask them to read this leaflet. You might ask them to tell you if they think your depression or anxiety is getting worse, or if they are worried about changes in your behaviour.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme. Website: www.mhra.gov.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine.
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