Creon 25000 Capsules, 100 Capsules

5.00 out of 5 based on 1 customer rating

Pancreatic enzyme supplement

Use only when directed by dietician or doctor

Prescription Product

  • Creon 25000 is a high strength pancreatic enzyme supplement.
  • Pancreatic enzyme supplement is used by people whose bodies do not make enough of their own enzymes to digest their food.


  • Creon 25000 is a high strength pancreatic enzyme supplement.
  • Pancreatic enzyme supplement is used by people whose bodies do not make enough of their own enzymes to digest their food.

Creon 25000 Capsules  100 Capsules

CREON 25000 Capsules is a pancreatic enzyme replacement therapy (PERT) that works by replacing the 3 pancreatic enzymes normally made by a healthy pancreas—lipase, protease, and amylase.

Your pancreas normally produces enzymes every time you eat, so CREON 25000 capsules needs to replace those enzymes every time you eat. Timing is key—CREON needs to be taken at the same time as food, with every meal and snack.

How does Creon 25000 work?

The enzymes in Creon 25000 work by digesting food as it passes through the gut. So you must take Creon 25000 at the same time as eating a meal or a snack. This will allow the enzymes to mix thoroughly with the food.

Further reading: What Is Pancreatic Enzyme Replacement Treatment (PERT).

What Is Pancreatic Enzyme Replacement Treatment (PERT).




What Is CREON?

CREON (pancrelipase) is a medicine used to treat people who cannot digest food normally because their pancreas does not make enough enzymes. This is a condition called exocrine pancreatic insufficiency (EPI) and may be due to cystic fibrosis, swelling of the pancreas that lasts a long time (chronic pancreatitis), removal of some or all of the pancreas (pancreatectomy), or other conditions.If you have EPI due to one of these conditions, CREON can help break down food into fats, proteins, and carbohydrates1 that your body can useIf you’re taking CREON, make sure you record what you’re eating, how you’re feeling, and when you take your enzymes. When you have a checkup, share this information with your doctor and discuss how your treatment plan is going.Creon is available over the counter, Creon 10000 and Creon Micro Granules.Creon available via your doctor's prescription, Creon 25000iuOver time, your doctor may adjust your dose to meet your changing needs.

How To use

How to take Creon 25000 capsules

  • Take the number of capsules as prescribed by your doctor or dietician.
  • Take Creon 25000 during or immediately after a meal or a snack and drink plenty of water.


Each Creon 25000capsule contains pancreatin PhEur 300 mg equivalent to:

Lipase25,000PhEur units
Amylase18,000PhEur units
Protease1,000PhEur units

Patient Information leaflets

The Patient Information Leaflet (PIL) of Creon 25000 capsules  is the leaflet included in the pack with a medicine

Click here

Warnings & Side Effects

Like all medicines, Creon 25000 capsules can cause side effects (unwanted effects or reactions), but not everyone gets them.

Side Effects of Creon 25000 capsules

If you have severe or long-lasting abdominal pain, contact your doctor immediately.

If you notice any unusual abdominal symptoms while taking Creon 25000 – contact your doctor.

Very common side effects (affect more than 1 in 10 patients):

  • stomach pains

Common side effects (affect 1-10 patients out of 100):

  • diarrhoea
  • constipation
  • feeling or being sick
  • bloating

Uncommon side effects (affect 1-10 patients out of 1000):

  • Skin reactions, such as a rash.

During use, some patients have also experienced the following, the frequency of which is unknown:

  • itching with or without a rash
  • allergic reactions (which may be severe)
  • severe or long-lasting abdominal pain (Fibrosing colonopathy).

At extremely high doses, some patients have had high levels of uric acid in their blood and urine.

Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system listed below.

In the UK:

The Yellow Card Scheme at:

Delivery Options

Delivery options

All deliveries are subject to the availability of the product and product sale conditions been met.

Order & Collect
Free next-day collection from In-Store

UK Delivery

Standard Delivery within the UK £3.50 Delivery time 3-4 days
First Class Delivery within the UK £5.90 Delivery time 1-2 days
Priority Delivery within the UK £7.10. Next day delivery by 1pm. Order must be placed by 1pm. Priority delivery is only available Monday to Thursday.

Europe Delivery

Standard Delivery within EEC from £12.50 Delivery time up to 5 days depending on the local delivery service within your country.
Expedited Delivery within EEC £39.50 Delivery time 2 days. Delivery by DHL, UPS or TNT.

Rest of the World

Standard Delivery Rest of the World from £16.10 Delivery Time 10 – 15 Days
Expedited Delivery Rest of the World £55.09 Delivery 5 days. Delivery service by DHL, TNT or UPS

For more information see our Shipping Policy or view our Return policy.

1 review for Creon 25000 Capsules, 100 Capsules

    • 5 out of 5
    Creon 25000 Capsules, 100 Capsules

    Ben Low (verified owner)

    Verified reviewVerified review - view originalExternal link

    I only need to take one with each meal instead of 2 or 3 Creon 10000.

    (0) (0)
    Creon 25000 Capsules, 100 Capsules

    Julie Cutbush

    Hello Ben. Thanks so much for your 5-star review! We’re glad to hear about positive experience using Creon and we hope to see you soon.

    Julie Cutbush
    Dock Pharmacy

Only logged in customers who have purchased this product may leave a review.

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